Soltan Hoseyn was the Safavid shah of Iran from 1694 to 1722. He was the son and successor of Shah Solayman (r. 1666–1694).

Born and raised in the royal harem, Soltan Hoseyn ascended the throne with limited life experience and more or less no expertise in the affairs of the country. He was installed on the throne through the efforts of powerful great-aunt, Maryam Begum, as well as the court eunuchs, who wanted to increase their authority by taking advantage of a weak and impressionable ruler. Throughout his reign, Soltan Hoseyn became known for his extreme devotion, which had blended in with his superstition, impressionable personality, excessive pursuit of pleasure, debauchery, and wastefulness, all of which have been considered by both contemporary and later writers as elements that played a part in the decline of the country.

The last decade of Soltan Hoseyn's reign was marked by urban dissension, tribal uprisings, and encroachment by the country's neighbours. The biggest threat came from the east, where the Afghans had rebelled under the leadership of the warlord Mirwais Hotak. The latters son and successor, Mahmud Hotak made an incursion into the country's centre, eventually reaching the capital Isfahan in 1722, which was put under siege. A famine soon emerged in the city, which forced Soltan Hoseyn to surrender on 21 October 1722. He relinquished his regalia to Mahmud Hotak, who subsequently had him imprisoned, and became the new ruler of the city. In November, Soltan Hoseyn's third son and heir apparent, declared himself as Tahmasp II in the city of Qazvin.