Already in 1794 and 1795 the revolutionary echoes from France reached Genoa, thanks to Genoese propagandists and refugees sheltered in the nearby state of the Alps, and in 1794 a conspiracy against the aristocratic and oligarchic ruling class that, in fact, was already waiting for it in the Genoese palaces of power. However, it was in May 1797 that the intent of the Genoese jacobins and French citizens to overthrow the government of the Doge Giacomo Maria Brignole took shape, giving rise to a fratricidal war in the streets between opponents and popular supporters of the current customs system.

The direct intervention of Napoleon (during the Campaigns of 1796) and his representatives in Genoa was the final act that led to the fall of the Republic in early June, who overthrew the old elites which had ruled the state for all of its history, giving birth to the Ligurian Republic on June 14, 1797, under the watchful care of Napoleonic France. After Bonaparte's seizure of power in France, a more conservative constitution was enacted, but the Ligurian Republic's life was short—in 1805 it was annexed by France, becoming the départements of Apennins, Gênes, and Montenotte.