The Peace of Callias is a purported peace treaty established around 449 BCE between the Delian League (led by Athens) and Persia, ending the Greco-Persian Wars. The peace was agreed as the first compromise treaty between Achaemenid Persia and a Greek city.

The peace was negotiated by Callias, an Athenian politician. Persia had continually lost territory to the Greeks after the end of Xerxes I's invasion in 479 BCE. The exact date of the treaty is debated, although it is usually placed after the Battle of the Eurymedon in 469 or 466 or the Battle of Cypriot Salamis in 450. The Peace of Callias gave autonomy to the Ionian states in Asia Minor, prohibited the encroachment of Persian satrapies within three days march of the Aegean coast, and prohibited Persian ships from the Aegean. Athens also agreed not to interfere with Persia's possessions in Asia Minor, Cyprus, Libya or Egypt (Athens at that time lost a fleet aiding an Egyptian revolt against Persia).