Shemyaka ruled inefficiently, did not manage to attract allies, and nobility started to defect from Moscow to Vologda. Vasily also managed to ally with Kazan Tatars. In the end of 1446, when Dmitry Shemyaka was out in Volokolamsk, the army of Vasily II entered Moscow. Vasily then started to chase Shemyaka. In 1447, they asked for peace, and agreed to accept the superiority of Vasily.

Nevertheless, Dmitry Shemyaka continued resistance, trying to attract the allies and to collect a big enough army to fight against Vasily. In 1448, Vasily started military action, which included mostly Northern lands up to Veliky Ustyug and with some interruptions continued till 1452, when Shemyaka was finally defeated and fled to Novgorod. In 1453, he was poisoned there following a direct order of Vasily. Subsequently, Vasily managed to remove all local princes who previously supported Shemyaka. The Principality of Mozhaysk and Serpukhov was made a part of the Grand Duchy of Moscow.