In 1513, Ponce de León led the first known European expedition to La Florida, which he named during his first voyage to the area. He landed somewhere along Florida's east coast, then charted the Atlantic coast down to the Florida Keys and north along the Gulf coast. In March 1521, Ponce de León made another voyage to southwest Florida with the first large-scale attempt to establish a Spanish colony in what is now the continental United States. However, the native Calusa people fiercely resisted the incursion, and Ponce de Léon was seriously wounded in a skirmish. The colonization attempt was abandoned, and he died from his wounds soon after returning to Cuba in early July.