Confederate forces across the South surrendered as news of Lee's surrender reached them. On April 26, 1865, the same day Boston Corbett killed Booth at a tobacco barn, General Joseph E. Johnston surrendered nearly 90,000 troops of the Army of Tennessee to Major General William Tecumseh Sherman at Bennett Place near present-day Durham, North Carolina. It proved to be the largest surrender of Confederate forces. On May 4, all remaining Confederate forces in Alabama, Louisiana east of the Mississippi River, and Mississippi under Lieutenant General Richard Taylor surrendered. The Confederate president, Jefferson Davis, was captured at Irwinsville, Georgia on May 10, 1865. On May 13, 1865, the last land battle of the war was fought at the Battle of Palmito Ranch in Texas.

On May 26, 1865, Confederate Lt. Gen. Simon B. Buckner, acting for General Edmund Kirby Smith, signed a military convention surrendering the Confederate trans-Mississippi Department forces. This date is often cited by contemporaries and historians as the end date of the American Civil War.