The Great Satraps' Revolt, or the Revolt of the Satraps (366-360 BCE), was a rebellion in the Achaemenid Empire of several satraps against the authority of the Great King Artaxerxes II Mnemon. The Satraps who revolted were Datames, Ariobarzanes and Orontes of Armenia. Mausolus the Dynast of Caria participated in the Revolt of the Satraps, both on his nominal sovereign Artaxerxes Mnemon's side and (briefly) against him.

They were supported by the pharaohs of Egypt, Nectanebo I, Teos, and Nectanebo II, to whom was sent Rheomithres who came back with 50 ships and 500 talents, and all joined forces against Artaxerxes II.